efficacy of the local endometrial injury in patients who had previous failed ivf-icsi outcome

background: the latest studies reported that local endometrial injury is a useful method to improve the success of ivf-icsi outcome. objective: to assess whether local endometrial injury occurred by pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent ivf-icsi cycle in patients who had recurrent ivf failure. materials and methods: an endometrial biopsy was performed on day 21st in 41 patients as intervention group in this retrospective cross-sectional study. the control group contained 42 women. results: implantation rate was 22.5% and 10.5% in intervention and control group, respectively and this difference was found to be statistically significant (p=001). pregnancy rate was 43.9% in the intervention group and this parameter was significantly lower in control group (21.4%) (p=0.03). conclusion: local endometrial injury in the nontransfer cycle increases the implantation rate and pregnancy rate in the subsequent ivf-icsi cycle in patients who had previous failed ivf-icsi outcome.